Chun-Shui Pan Selected Research

qishen yiqi

1/2022	QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.
1/2021	QiShenYiQi Pills Attenuates Ischemia/Reperfusion-Induced Cardiac Microvascular Hyperpermeability Implicating Src/Caveolin-1 and RhoA/ROCK/MLC Signaling.
1/2021	QiShenYiQi Inhibits Tissue Plasminogen Activator-Induced Brain Edema and Hemorrhage after Ischemic Stroke in Mice.
1/2019	Effects and mechanisms of QiShenYiQi pills and major ingredients on myocardial microcirculatory disturbance, cardiac injury and fibrosis induced by ischemia-reperfusion.
1/2019	QiShenYiQi Pills® ameliorates ischemia/reperfusion-induced myocardial fibrosis involving RP S19-mediated TGFβ1/Smads signaling pathway.
1/2019	A novel traditional Chinese medicine ameliorates fatigue-induced cardiac hypertrophy and dysfunction via regulation of energy metabolism.
1/2018	The Contribution of Different Components in QiShenYiQi Pills® to Its Potential to Modulate Energy Metabolism in Protection of Ischemic Myocardial Injury.
1/2017	QiShenYiQi Pills, a Compound Chinese Medicine, Prevented Cisplatin Induced Acute Kidney Injury via Regulating Mitochondrial Function.
7/2015	QiShenYiQi Pills, a compound in Chinese medicine, protects against pressure overload-induced cardiac hypertrophy through a multi-component and multi-target mode.
9/2013	QiShenYiQi Pills® prevent cardiac ischemia-reperfusion injury via energy modulation.

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Chun-Shui Pan Research Topics

Disease

20	Ischemia 01/2024 - 04/2010
12	Edema (Dropsy) 06/2022 - 09/2013
10	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 09/2004
8	Fibrosis (Cirrhosis) 11/2022 - 05/2006
8	Cardiomegaly (Heart Hypertrophy) 01/2022 - 05/2006
8	Reperfusion Injury 01/2021 - 09/2013
6	Myocardial Ischemia (Ischemic Heart Diseases) 01/2021 - 09/2005
5	Hemorrhage 01/2024 - 12/2016
4	Lung Injury 05/2024 - 11/2014
4	Inflammation (Inflammations) 05/2024 - 01/2019
4	Infarction (Infarctions) 01/2024 - 05/2006
4	Myocardial Infarction 11/2022 - 04/2010
4	Body Weight (Weight, Body) 01/2022 - 01/2012
4	Hypertension (High Blood Pressure) 01/2013 - 02/2004
4	Heart Failure 11/2006 - 09/2004
3	Cerebral Infarction 01/2024 - 06/2015
3	Hypoxia (Hypoxemia) 01/2022 - 01/2018
3	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2022 - 10/2014
3	Brain Edema (Cerebral Edema) 01/2021 - 06/2015
3	Ischemic Stroke 01/2021 - 06/2015
3	Hypertrophy 01/2019 - 09/2005
3	Necrosis 01/2017 - 01/2005
3	Sepsis (Septicemia) 12/2016 - 05/2004
2	Infections 05/2024 - 06/2022
2	Colitis 01/2024 - 01/2013
2	Stroke (Strokes) 01/2024 - 01/2021
2	Cerebral Hemorrhage 01/2024 - 01/2018
2	Neoplasms (Cancer) 10/2023 - 01/2019
2	Neoplasm Metastasis (Metastasis) 10/2023 - 01/2019
2	Rupture 01/2021 - 09/2013
2	Cognitive Dysfunction 01/2018 - 01/2018
2	Acute Lung Injury 12/2016 - 11/2014
2	Septic Shock (Toxic Shock Syndrome) 07/2010 - 05/2004
2	Vascular Calcification 07/2005 - 07/2005
2	Vascular Remodeling 10/2004 - 09/2004
1	Weight Loss (Weight Reduction) 01/2024
1	Enteritis 01/2024
1	Coronary Artery Disease (Coronary Atherosclerosis) 11/2022

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 01/2024 - 05/2004
12	qishen yiqiIBA 01/2022 - 01/2012
11	AlbuminsIBA 01/2024 - 01/2013
9	Messenger RNA (mRNA)IBA 11/2013 - 02/2004
8	Evans Blue (Blue, Evans)FDA Link 01/2024 - 06/2015
8	Adenosine Triphosphate (ATP)IBA 06/2022 - 01/2013
7	CytokinesIBA 05/2024 - 10/2014
7	CollagenIBA 01/2019 - 11/2004
5	Claudin-5IBA 01/2024 - 12/2016
4	OccludinIBA 01/2024 - 01/2018
4	Cardiotonic Agents (Cardiac Stimulants)IBA 11/2022 - 04/2010
4	LipopolysaccharidesIBA 01/2019 - 02/2014
4	Adenosine Monophosphate (AMP)IBA 01/2018 - 01/2013
3	Interleukin-6 (Interleukin 6)IBA 05/2024 - 01/2019
3	Matrix Metalloproteinases (MMPs)IBA 01/2024 - 01/2019
3	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2024 - 01/2018
3	EnzymesIBA 10/2023 - 01/2005
3	astragaloside AIBA 06/2022 - 11/2013
3	cadherin 5IBA 01/2022 - 01/2017
3	notoginsenoside R1IBA 01/2021 - 01/2014
3	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 06/2015
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2019 - 01/2013
3	Insulin (Novolin)FDA Link 01/2019 - 01/2015
3	Sirtuin 3IBA 01/2019 - 08/2015
3	src-Family KinasesIBA 01/2018 - 06/2015
3	Adenosine Diphosphate (ADP)IBA 01/2018 - 09/2013
3	AdrenomedullinIBA 07/2010 - 05/2004
3	Isoproterenol (Isoprenaline)FDA LinkGeneric 11/2006 - 01/2005
3	Peptides (Polypeptides)IBA 09/2005 - 02/2004
2	ferric chlorideIBA 01/2024 - 01/2021
2	CateninsIBA 01/2024 - 01/2022
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2023 - 01/2019
2	ImmunosorbentsIBA 10/2023 - 01/2019
2	SirtuinsIBA 01/2021 - 08/2015
2	Connexin 43 (Connexin43)IBA 01/2021 - 01/2019
2	Actins (F Actin)IBA 01/2021 - 01/2018
2	Caveolin 1IBA 01/2021 - 01/2017
2	AntioxidantsIBA 01/2019 - 06/2015
2	oxidized low density lipoproteinIBA 01/2019 - 01/2018
2	Hematoxylin (Haematoxylon)IBA 01/2019 - 02/2014
2	Eosine Yellowish-(YS) (Eosin)IBA 01/2019 - 02/2014
2	salvianolic acidIBA 01/2019 - 10/2014
2	Laminin (Merosin)IBA 01/2018 - 12/2016
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2017 - 10/2014
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2013 - 04/2010
2	ApelinIBA 07/2010 - 01/2006
2	GhrelinIBA 05/2006 - 07/2005
2	Neprilysin (Neutral Endopeptidase)IBA 01/2005 - 05/2004
2	AldosteroneIBA 11/2004 - 10/2004
1	GW 4064IBA 05/2024
1	Poly I-CIBA 05/2024
1	Pattern Recognition ReceptorsIBA 05/2024
1	liquiritinIBA 05/2024
1	xihuangIBA 01/2024
1	isothiocyanic acidIBA 01/2024
1	Fluorescein (Funduscein)FDA LinkGeneric 01/2024
1	Interleukin-10 (Interleukin 10)IBA 10/2023

Therapy/Procedure

6	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022 - 10/2014
4	Therapeutics 01/2024 - 12/2016
2	Lasers (Laser) 01/2013 - 01/2012
1	Oral Administration 01/2024
1	Stents 11/2022